ABSTRACT
The current outbreak of COVID-19 infection among humans is strongly impacting global physical and mental health. This outbreak can induce or exacerbate some chronic disorders such as functional gastrointestinal disorders (FGIDs) due to stress, anxiety, depression, insomnia, denial, anger, and fear. The current focus on the physical aspects of COVID-19 infection may distract public attention from the psychosocial consequences of this outbreak. The mental disorders related to this outbreak may develop and extend FGIDs in the long term. FGIDs have a significant impact on daily activities and quality of life and also cause high economic burdens through direct medical costs and loss of productivity. The purpose of this mini-review was to emphasize the critical state of old and new cases of FGIDs during the COVID-19 outbreak. Published English papers about mental health disorders related to the COVID19 outbreak or before the infectious outbreak, stress, and FGIDs were considered and reviewed. We selected articles which were current and had the most relevance to FGIDs, psycho-somatization, and infectious outbreak.